Time to Invest in Sickle Cell Anemia as a Global Health Priority.
نویسنده
چکیده
DOI: 10.1542/peds.2016-0348 Accepted for publication Mar 16, 2016 Address correspondence to Patrick T. McGann, MD, MS, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229. E-mail: [email protected] PEDIATRICS (ISSN Numbers: Print, 0031-4005; Online, 10984275). Copyright © 2016 by the American Academy of Pediatrics FINANCIAL DISCLOSURE: The author has indicated he has no fi nancial relationships relevant to this article to disclose. FUNDING: This work was supported by the National Heart, Lung, and Blood Institute Award K23-HL128885-01. The content is solely the responsibility of the authors and does not necessarily represent the offi cial views of the National Institutes of Health. Funded by the National Institutes of Health (NIH). POTENTIAL CONFLICT OF INTEREST: The author has indicated he has no potential confl icts of interest to disclose. More than 500 children with sickle cell anemia (SCA) die every single day because of lack of access to early diagnosis and associated treatment, yet SCA remains an invisible global health problem.
منابع مشابه
Results of Transcranial Doppler in Children with Sickle Cell Disease: Correlation between the Time-Averaged Mean of Maximum Velocity and Some Hematological Characteristics
Abstract Background: Transcranial Doppler ultrasonography results have not been previously studied in among Iranian sickle cell anemia patients. The present study was performed to evaluate the pattern of intracranial flow velocities among Iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial...
متن کاملThe Effect of L-Glutamine on Pain Crisis Reduction in Patients with Sickle Cell Anemia and Sickle β°-Thalassemia
Background: A low level of L-glutamine, a precursor of nicotinamide adenine dinucleotide (NAD) in red blood cells (RBCs), is identified as an underlying mechanism for the potential decrement of the NAD redox and the incidence of pain crisis in sickle cell anemia (SCA). The aim of this study is to assess the impact of oral L-glutamine therapy on pain crisis reduction in patients with SCA and sic...
متن کاملEffect of Non- pharmacological Palliative Methods Training on Sickle Cell Anemia Outcomes
Background Drugs used by patients with sickle cell anemia to relieve pain have side effects, so the use of non-pharmacological palliative methods (such as massage, muscle relaxation, heat, drinking fluids, etc.) can be considered. We aimed to determine effect of non-pharmacological palliative methods training among adolescents with sickle cell anemia. <stro...
متن کاملSide Effects of Hydroxyurea in Patients with Sickle Cell Anemia
Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...
متن کاملThe Influence of Fetal Hemoglobin on Clinical and Hematological Variables of Children and Adolescents with Sickle Cell Anemia in Basra, Southern Iraq
Background: There are many parameters that modulate the severity of sickle cell anemia. Fetal hemoglobin (Hb F) is one of these major variables. However, its effect is clinically inconsistent. We conducted a descriptive study to assess the influence of Hb F on clinical events and hematological variables in patients with sickle cell anemia. Methods: 151 patients with sickle cell anemia with a st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Pediatrics
دوره 137 6 شماره
صفحات -
تاریخ انتشار 2016